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Ben Greenfield10 January 2025

Episode 414: Ben Greenfield: Biohacking Sleep Deprivation with NAD and Creatine

2Frameworks
6Insights

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Frameworks in this episode

Insights & moments

The myth-busts, hot takes, explainers, and tools worth keeping.

Hot Take· 1

Hot Take02:30

Why Greenfield Prefers Full-Fat Dairy to Skim Milk

Greenfield argues that dairy should be evaluated as a whole food rather than reduced to calories alone. He prefers full-fat dairy because he says the evidence for metabolic function, satiety, brain function, and bone health is stronger than for low-fat or fat-free versions.

  • The calorie advantage of skim milk is only one dimension
  • Greenfield associates dairy fat with satiety and metabolic function
  • He compares removing dairy fat with removing egg yolks or chicken skin
  • The broader food matrix matters alongside protein and calories

all the studies on the benefits of dairy tend to be much stronger with full fat Dairy compared to lowfat fat-free dairy

Ben Greenfield · 02:00

it's more than just calories and obviously if we're talking about calories yeah skim milk

Ben Greenfield · 02:30
#dairy#dietary fat#satiety#whole foods

Explainer· 2

Explainer01:00

Why Greenfield Worries Less About Rings Than Phones and Wi-Fi

Greenfield distinguishes low-power Bluetooth wearables from higher-priority radio-frequency exposures. He still wears a ring because he considers its signal comparatively minor, while acknowledging that devices placed beside the head for long periods are a different exposure pattern.

  • A ring’s Bluetooth signal is described as low power
  • Distance and placement affect the exposure pattern
  • Greenfield prioritises Wi-Fi and phone radio frequencies over rings
  • He continues to use a wearable ring

a class 3 Bluetooth signal is not a big like maybe if you had it next to your head like airpod inside your ear all…

Ben Greenfield · 01:00

Bluetooth is way less of important of a fish to fry compared to like Wi-Fi and radio frequencies from phones Etc

Ben Greenfield · 01:00
#emf#bluetooth#wearables#risk
Explainer05:00

The Protein Difference Behind Goat, Camel, and A2 Milk

Greenfield describes camel milk as lower in lactose and containing a smaller, more bioavailable protein than cow’s milk. He also connects goat and camel milk with an A2-like protein profile, which he says tends to produce less of an immune response than A1-heavy cow’s milk.

  • Camel milk is described as lower in lactose
  • Its protein is presented as smaller than cow’s-milk protein
  • A2-labelled cow’s milk is intended to reduce A1 protein exposure
  • Goat and camel milk are described as naturally more A2-like

lower amounts of lactose a smaller Protein that's more bioavailable than the larger protein found in cow's milk

Ben Greenfield · 05:00

Camel's milk and goats milk are naturally more like an A2 they have less of the A1 based protein

Ben Greenfield · 05:30
#goat milk#camel milk#a2 protein#dairy

Tool· 1

Tool00:00

Ben Greenfield’s Favourite Stack for Sleep Deprivation

Greenfield names NAD-related precursors and creatine as his preferred combination for periods of sleep deprivation. He also links NR products with cognition, focus, brain fog, and mitochondrial health, although the excerpt does not provide dosage or safety guidance.

  • The stack combines an NAD precursor with creatine
  • NR, NAD, and NMN are grouped as related options
  • The excerpt makes no dosing recommendation
  • The claim is presented as Greenfield’s personal preference

my favorite stack for sleep deprivation is NR NAD or nmn which are all just like NAD precursors and creatine

Ben Greenfield · 00:00
#sleep deprivation#nad#creatine#supplements

Takeaway· 2

Takeaway04:00

Lactose Intolerance Does Not Always Mean Giving Up Dairy

Greenfield says some lactose-intolerant people tolerate fermented dairy better, particularly yoghurt and kefir. He also points to goat and camel milk as alternatives with less lactose, while explaining that added lactase digests lactose rather than literally removing it at manufacture.

  • Fermentation can make dairy easier for some people to tolerate
  • Yoghurt and kefir are the primary fermented options named
  • Goat and camel milk are described as lower-lactose alternatives
  • Added lactase helps digest the lactose present

I can have dairy if it's fermented and this is the case for many people if you ferment the dairy if you do like a…

Ben Greenfield · 04:00

You Can Do Better If you're lactose intolerant you can also do better on milks that have lower amounts of lactose sugar like goat milk…

Ben Greenfield · 04:30
#lactose#fermentation#yoghurt#milk
Takeaway06:00

Nut Milk Trades Dairy Tolerance for Additive and Calorie Checks

Greenfield says nut milks can suit people who do not tolerate dairy and can reduce calories, but the label still matters. Added cane sugar, thickeners, fillers, and carrageenan can weaken the trade, while varieties such as macadamia milk may be higher in calories.

  • Nut milks may be easier to tolerate than dairy
  • Many varieties are lower calorie, but not all
  • Added sugar, thickeners, and fillers should be checked
  • Carrageenan may upset some people’s stomachs

one issue is if you want to be careful with your calorie count a nut milk is a better substitute compared to a Dairy Milk

Ben Greenfield · 06:00

no caragan right that is a fill that can upset a lot of people's stomachs

Ben Greenfield · 06:00
#nut milk#food labels#carrageenan#calories