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Dr. Josh Axe16 September 2025

Episode 485: Dr. Josh Axe: Why Your Healthy Smoothie is Making You Sick (And What Actually Heals)

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The myth-busts, hot takes, explainers, and tools worth keeping.

Myth Buster· 3

Myth Buster06:30

Why a Healthy Smoothie May Backfire on Hypothyroidism

Axe argues that people with hypothyroidism often run cold and may not respond well to a diet dominated by cooling smoothies and salads. He recommends considering warmer soups, teas, cooked vegetables, ginger, and cinnamon instead, while framing the choice as individual rather than universal.

  • Hypothyroidism is associated in the discussion with low body temperature
  • Smoothies and salads are characterized as cooling foods
  • Soups, teas, squash, ginger, and cinnamon are suggested as warming alternatives
  • The recommendation depends on the person's condition

salads and superfood smoothies are terrible for people with hypothyroidism.

Dr. Josh Axe · 06:30

So rather than smoothies and and uh salads, you should be doing soups and teas.

Dr. Josh Axe · 22:30
#hypothyroidism#smoothies#warming foods#nutrition
Myth Buster35:00

Bread Is Not the Villain—Bad Processing Is

Axe distinguishes modern refined bread from bread made with ancient grains, sprouting, stone grinding, fermentation, and sourdough methods. He says soaking or fermenting reduces phytic acid and improves nutrient availability, while clarifying that he is not broadly endorsing bread.

  • Modern bread is criticized for refined grain and synthetic fortification
  • Ancient grains such as wheat, barley, and rye are discussed
  • Sprouting and fermentation are said to reduce phytic acid
  • His practical rule is sourdough made from ancient grains

bread is not a villain and if you're going to eat bread eat sourdough from ancient grains.

Dr. Josh Axe · 37:30

When you sprout or ferment, unlock all the nutrients and now you're absorbing all of it.

Dr. Josh Axe · 36:30
#bread#sourdough#ancient grains#fermentation
Myth Buster1:39:00

Most People Do Not Need a 5:1 Sodium Electrolyte Mix

Axe argues that popular high-sodium electrolyte mixes are designed for people who sweat heavily, not ordinary daily activity. For many people he prefers a ratio closer to equal sodium and potassium, using coconut water plus sea salt as a simple example.

  • One popular formula is described as a 5:1 sodium-to-potassium ratio
  • Axe prefers closer to 1:1 for many ordinary users
  • Heavy sweaters and endurance athletes may need a different ratio
  • Coconut water and sea salt provide a simpler alternative

For my most people I work with, it should probably be closer to a 1:1 ratio of an electrolyte drink.

Dr. Josh Axe · 1:39:30

Coconut water, throw sea salt in there. There you go. There's your electrolyte drink.

Dr. Josh Axe · 1:39:30
#electrolytes#sodium#potassium#hydration

Hot Take· 2

Hot Take51:30

Ordinary Sadness Is Not Always a Disorder

Axe argues that some children and adults are medicated for emotions or classroom behavior that may be normal parts of life. He links rising mental-health problems to misdiagnosis, loss of purpose, weak identity, and less community or spiritual connection.

  • He questions expecting boys to sit still in classrooms all day
  • Feeling sad or down is sometimes normal
  • Purpose and identity are presented as protective factors
  • He criticizes medication that does not address an underlying cause

Sometimes you should feel sad sometimes you should be down.

Dr. Josh Axe · 53:00

are we supposed to take boys and just shove them in a classroom for eight hours and say just sit there and don't move.

Dr. Josh Axe · 52:00
#mental health#adhd#purpose#medication
Hot Take1:15:30

Why Axe Opposes Full-Dose GLP-1s

Axe and Cohen criticize heavy GLP-1 use for producing weight loss without behavior change and potentially reducing muscle mass. Axe distinguishes full dosing from microdosing, saying he strongly opposes the former while regarding the latter as less harmful but still not his preferred fix.

  • The discussion raises muscle loss during GLP-1 weight reduction
  • Both speakers describe a skinny-fat outcome
  • Axe prefers protein, fiber, and lifestyle change
  • He says evidence for microdosing claims is insufficient

one study found 40% of the of the mass they're losing is muscle mass

Dr. Josh Axe · 1:15:30

I don't think there's enough research on any of that or understanding how it works physiologically to for us to make a lot of big…

Dr. Josh Axe · 1:22:30
#glp-1#weight loss#muscle mass#behavior change

Explainer· 4

Explainer12:00

Stress Can Hit the Gut as Hard as Food

Axe recounts patients whose bowel symptoms flared despite following their diet because divorce, bereavement, or work pressure had intensified. His broader point is that emotional and lifestyle stress can be a major physical-health input rather than a secondary detail.

  • Diet adherence did not prevent every gut flare in his clinic stories
  • Divorce, grief, and work stress coincided with symptoms
  • Stress is presented as comparable to diet in its bodily impact
  • Lifestyle assessment should accompany food assessment

stress can impact your body in an even greater way or an equal way to to to diet.

Dr. Josh Axe · 13:00

I truly believe that stress is the number one thing that makes people sick.

Dr. Josh Axe · 12:00
#stress#gut health#ibs#emotions
Explainer39:30

The A1 vs A2 Dairy Difference

Axe explains that dairy tolerance may depend on the cow's casein type as well as pasteurization, fermentation, and homogenization. He contrasts common A1 cow's milk with A2 proteins found predominantly in sheep, goats, human milk, and specifically marketed A2 dairy.

  • A1 casein is described as more inflammatory for some people
  • Goat and sheep dairy predominantly contain A2 casein
  • Pasteurization removes bacteria and enzymes
  • Fermentation and homogenization also change the final food

people can buy today A2 dairy, which has the right genetic components of in terms of the protein.

Dr. Josh Axe · 41:00

The bacteria are 99.9999999% of the time good bacteria that you need for digestion.

Dr. Josh Axe · 41:00
#dairy#a2 milk#casein#digestion
Explainer1:24:00

Why Pomegranate Is Axe's Top Healing Fruit

Axe selects pomegranate as his preferred fruit for healing because of its fiber, antioxidants, and ellagic acid. He says gut conversion can produce several urolithins associated with mitochondrial recycling, giving the whole food a broader compound profile than a single urolithin A supplement.

  • Pomegranate is high in fiber and antioxidants
  • Ellagic acid can be converted into multiple urolithins
  • The compounds are linked in the discussion to mitochondrial biogenesis
  • A whole-food source offers more compounds than one isolated supplement

pomegranates to me are probably my favorite fruit for healing.

Dr. Josh Axe · 1:26:00

You're going to get a much much wider range in benefits than taking just a plain old ureiththna supplement.

Dr. Josh Axe · 1:25:30
#pomegranate#mitochondria#ellagic acid#fruit
Explainer1:30:00

What the Tongue Can Reveal in Chinese Medicine

Axe demonstrates a traditional Chinese-medicine tongue assessment, reading edge ridges, pallor, coating, and color as clues about digestion, blood deficiency, dampness, or heat. He pairs this observational method with symptoms and laboratory tests rather than presenting it as his only source of information.

  • Edge ridges are interpreted as digestive weakness
  • A pale tongue is associated with blood deficiency
  • Tongue coating is linked to dampness or candida
  • Axe also uses micronutrient, hormone, and GI-map tests

The number one test is looking at your tongue.

Dr. Josh Axe · 1:29:30

your tongue will tell me the exact herbs you need to take.

Dr. Josh Axe · 1:30:30
#tongue diagnosis#chinese medicine#testing#digestion

Story· 1

Story42:00

Jordan Rubin's 40-Day Diet and Prayer Story

Axe tells how Jordan Rubin became severely ill with Crohn's disease and ulcerative colitis, traveled widely seeking help, and then followed a Bible-inspired diet while living in an RV in California. He says Rubin ate a narrow set of foods, prayed daily, recovered, and later founded Garden of Life.

  • Rubin reportedly lost about 80 pounds during severe illness
  • A naturopathic practitioner invited him to California
  • The protocol emphasized fermented dairy and a limited diet
  • Axe says the experience inspired Rubin's natural-health career

he spent every day and night praying for healing.

Dr. Josh Axe · 42:30

Jordan rent in an RV, went out, moved to California, just lived in an RV, followed this protocol, uh, and completely cured his Crohn's and…

Dr. Josh Axe · 44:30
#jordan rubin#crohns#garden of life#healing story

Tool· 1

Tool1:00:30

Axe's Essential-Oil Use Cases

Axe maps several oils to specific uses while warning that they are not miracle cures. He mentions lavender for sleep, holy basil for stress, citrus-peel oils for calming and digestion, helichrysum for scarring, and frankincense for immune-related use.

  • Lavender is discussed for sleep
  • Holy basil or tulsi is described as an adaptogen
  • Orange and other citrus oils are linked to calming effects
  • Topical use and study doses are discussed separately

unless you're really deficient in something, I don't think they're a miracle or a cure in a lot of cases.

Dr. Josh Axe · 1:00:30

Holy basil. That's a good one that was known as Tulsi as well. That's great for stress relief.

Dr. Josh Axe · 1:01:30
#essential oils#lavender#tulsi#sleep