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Dr. Stacy Sims25 March 2025

Episode 435: Dr. Stacy Sims: Workout Like a Woman Not a "Little Man" + How To Train Based on Hormones

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The myth-busts, hot takes, explainers, and tools worth keeping.

Myth Buster· 2

Myth Buster44:00

Beet Juice May Help Postmenopause but Backfire Before It

Sims rejects beet juice as a universal performance aid for women. She says nitrate supplementation may support vasodilation and VO2 max after menopause, but before menopause it can interfere with estrogen-linked vascular regulation and contribute to poor blood-pressure control.

  • Supplement effects can change by reproductive stage
  • Beet juice may improve vasodilation postmenopause
  • Premenopausal estrogen already participates in nitric-oxide regulation
  • Added nitrates may impair blood-pressure control before menopause

For post-menopausal women, sweet, it works well. It helps with vasoddilation. It helps improve V2 max.

Dr. Stacy Sims · 44:00

But for uh premenopausal women, including pmenopause, it has a a backwards effect

Dr. Stacy Sims · 44:30
#beet juice#nitrates#menopause#blood pressure
Myth Buster1:01:00

Women May Get More From Cool Water Than an Ice Plunge

Sims says ice-cold plunges can be too strong a sympathetic stressor for women, increasing cortisol, blood glucose, and free fatty acids. Water around 15°C may allow the initial shock to give way to vagal and parasympathetic calming instead.

  • Recommended cool-water temperature is around 15°C
  • Ice can cause excessive sympathetic drive and constriction
  • Cool water may better stimulate vagal calming
  • Heat may offer women more benefits than cold immersion

When we think about cold plunge for women, it's cool water. It's around 15° C, which is around that 56 57° Fahrenheit mark.

Dr. Stacy Sims · 1:01:00

Ice is too cold and we don't get the same kind of response that men do when we get into ice.

Dr. Stacy Sims · 1:01:00
#cold plunge#cool water#stress response#women

Hot Take· 1

Hot Take48:00

Ozempic Is an Obesity Tool, Not a Vanity-Pound Shortcut

Sims sees GLP-1 medication as a tool for significant weight loss and appetite-noise reduction, provided it creates room to build sustainable habits. She warns that lean mass and bone can be lost and rejects casual microdosing for a small cosmetic weight change.

  • Lean mass and bone loss need active attention
  • GLP-1s can reduce food noise in significant obesity
  • The opportunity is to install lifting and healthier food habits
  • Small vanity-weight goals do not justify casual use

When we start looking at Osimpic as a tool in the toolbox for losing a significant amount of weight, not our vanity pounds of 10…

Dr. Stacy Sims · 48:30

it can help with appetite control to dampen the noise, the food noise that happens so much around the ultrarocessed food and the cravings

Dr. Stacy Sims · 48:30
#ozempic#glp-1#weight loss#lean mass

Explainer· 4

Explainer04:30

Why Women and Men Start With Different Muscle-Fiber Advantages

Sims says XX bodies tend to begin with more endurance-oriented, oxidative fibers, while XY bodies tend to have more fast-twitch, power-oriented fibers. She argues that women's training should therefore preserve endurance while deliberately developing speed and power across life.

  • XX physiology tends toward aerobic, fatigue-resistant muscle fibers
  • XY physiology tends toward fast-twitch, glycolytic fibers
  • Women may need more deliberate power and speed development
  • Training protocols derived from men may transfer poorly

If you are born XX then you have more endurance type fibers.

Dr. Stacy Sims · 04:30

When we look at XY, they're born with more of the fast twitch glycolytic powerbased fibers.

Dr. Stacy Sims · 05:00
#sex differences#muscle fibers#physiology#training
Explainer05:00

Puberty Changes How Girls Need to Run, Jump, and Land

Estrogen and other hormonal changes alter girls' center of gravity, hip width, and shoulder girdle. Sims argues that girls are rarely retaught movement after these changes, which can leave them feeling awkward and contribute to sport dropout.

  • Center of gravity shifts toward the hips
  • Hips and shoulder girdle widen
  • Movement skills should be retaught after biomechanical change
  • Sport dropout may reflect mechanics, not motivation alone

So our center of gravity goes from being up in the chest area down to the hip area.

Dr. Stacy Sims · 05:30

We aren't taught how to run again, how to jump, how to swing, how to land, or any of those things.

Dr. Stacy Sims · 05:30
#puberty#biomechanics#girls sport#movement
Explainer11:00

The Female Mechanics Behind Frozen Shoulder Risk

Sims links frozen shoulder risk to wider female shoulder mechanics combined with age-related changes in estrogen, progesterone, tendons, and bursa. Narrow grip and shoulder-hitching conventions based on male physiology may add strain during push-ups, pull-ups, and overhead work.

  • Women's shoulder girdles are wider
  • Narrow grip conventions may create strain
  • Hormonal change affects tensile strength and tissue texture
  • Perimenopause can amplify existing movement mismatches

Same with push-ups. They're trying to teach you to be really tight and use more tricep, but our shoulders as women, we need to be…

Dr. Stacy Sims · 11:30

And you couple that with changes in our estrogen progesterone ratio which changes tensile strength and the actual texture kind of of our tendons and…

Dr. Stacy Sims · 12:00
#frozen shoulder#perimenopause#shoulder#biomechanics
Explainer40:00

Plant Protein Works When Total Intake and Leucine Are Covered

Sims says plant-based muscle building depends on sufficient total daily protein and a complete spread of essential amino acids, not perfect protein combinations at every meal. Post-exercise leucine matters, so pea protein isolate may require a slightly larger dose than whey.

  • Daily protein total matters more than complete protein at every meal
  • Essential amino acids can come from mixed plant foods
  • Leucine content matters after exercise
  • Pea protein may need a larger serving than whey

but it's not about that it's about the total amount of protein you have through the day and making sure that you have all your…

Dr. Stacy Sims · 40:00

the important part yes is leucine content post exercise

Dr. Stacy Sims · 40:00
#plant protein#leucine#amino acids#nutrition

Q&A· 1

Q&A53:30

Your 20s and 30s Are for Experimenting—Without Dropping Strength

Sims says younger women can explore endurance goals and different activities, while accounting for contraception, cycle patterns, and stress signals. Whatever the sport, she recommends retaining some strength training to build a resilient base.

  • Hormonal contraception can affect training response
  • Cycle and bleed-pattern changes can warn of excessive stress
  • Periodize cardiovascular and strength work
  • Keep some strength training even when endurance is the main goal

This is a time Yeah. Well, this is a time where you can play. You can play a little bit. You can try a lot…

Dr. Stacy Sims · 53:30

But put some strength training in there. You don't have to put it your main stay, but you want to have a strong, resilient body…

Dr. Stacy Sims · 54:00
#women in 20s#women in 30s#periodization#strength

Tool· 1

Tool1:00:30

A Small Sauna Dose Can Deliver Broad Health Benefits

Sims recommends heat exposure and says a Finnish sauna can produce cardiovascular, blood-pressure, metabolic, gut, and brain benefits. The session does not need to be long, but the body must become genuinely hot and begin sweating for the adaptation signal.

  • Ten to 15 minutes can be sufficient
  • Three weekly sessions are the suggested dose
  • Heat may improve cardiovascular and metabolic control
  • Infrared heat must still trigger uncomfortable warmth and sweating

It could be 10 to 15 minutes in a finished sauna three times a week.

Dr. Stacy Sims · 1:00:30

But you need that. You need that uncomfortable heat and uncomfortable sweating to invoke the change.

Dr. Stacy Sims · 1:04:30
#sauna#heat therapy#cardiovascular health#metabolic health

Takeaway· 1

Takeaway38:00

Why Women's Protein Needs Rise Around Age 40

Women become more resistant to the muscle-building effects of exercise and protein from roughly age 40, according to Sims, earlier than men. She recommends substantially more protein for active adults than the minimum intake designed merely to prevent malnutrition.

  • Women's anabolic resistance can begin around age 40
  • A stronger resistance-training dose is needed
  • Protein recommendations based on malnutrition prevention are too low for active people
  • Sims cites one to 1.1 grams per pound for active people

We see that when women start to hit 40 onwards, we are more what's called anabolically resistant to exercise and protein.

Dr. Stacy Sims · 38:00

For men, that starts about 50 55.

Dr. Stacy Sims · 38:00
#protein#anabolic resistance#women over 40#lean mass